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KMID : 0374919930140010095
Inje Medical Journal
1993 Volume.14 No. 1 p.95 ~ p.106
A Study on the Effectiveness of Disinfectants on Hepatitis B Virus in Vitro for Contaminated Blood
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Abstract
Contaminated blood with microorganism and virus is put into the environment without any discontamination treatment. It may give rise to a serious health and sanitation problems and also to a threat of spreading infectious disease.
In order to select the appropriate disinfectant and disinfection procedure, the tests performed in vitro via artificially contaminated blood with hepatitis B surface antigen(HBs Ag) positive plasma using several disinfectants commonly used in
hospitals.
The tested disinfectants were sodium hypochlorite(NaOCL), sodium dichloroisocyanurate (NaDCC), ethyl alcohol(EtOH), povidon iodine, cresol soap, benzalkonium chloride, mono-lauryl-di(aminoethyl) glycin HCI(MLDGH) and glutaradehyde. The HBs Ag
inactivation study was performed using the Radioimmunoassary(RIA) method.
@ES The results were as follows;
@EN The inactivation effect of the HBs Ag of the benzalkonium chloride, glutaradehyde, MLDGH, and NaOCL was 98.6%, 92.3%, 88.6% and 68.8%with in 5 hours after disinfectin on the same 2% concentration, respectively.
In conclusion, this study provided useful information for the 2% benalkonium chloride is the best disinfectants in consideration of the chemical stability, economy, and saniation.
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